Cialis is modern and effective medicine used for treatment of different stages of erectile dysfunction. This medicine results the dilation of blood vessels of penis and enhances blood flow to it. Thank to this fact it provides long-lasting erection. Well-known medicines like Viagra and Levitra have the same effect.

History of the creation of Cialis was launched in 1992 when scientists researched properties of sildenafil citrate – it is the main ingredient of well-known Viagra. Originally it was planned to use sildenafil for treatment of heart diseases and blood vessels, but all the men, who took part in these tests, noted the strong side effect – a long-lasting erection.

Direct effect of the medicine on the cardiovascular system was insignificant. In 1996, sildenafil was patented as a medicine for treatment of ED, and 2 years later it was approved for use by the Ministry of Health of USA. From that moment the epoch of medicine treatment of erectile dysfunction was started. Many scientists think that the invention of inhibitors of phosphodiesterase-5 is very important as invention of antibiotics and X-rays! In 1998 inventors of Viagra got Nobel Prize for their discovery.

However, soon it turned out that Viagra does not help every man, its effect is limited to 4-6 hours, and fatty foods and alcohol prevent the absorption of medicine and reduce the effect. So, scientists began to search new measures to improve erection and soon Cialis was invented. Due to the modification of the molecule that is the base of all inhibitors of phosphodiesterase-5, it was created Cialis. It is stronger medicine than Viagra, its duration is 36 hours and it absorbs regardless of fatty foods and alcohol intake.

Cialis is just a «young» medicine, because it appeared on the pharmacological market in 2003. After the active ingredient of the medicine – tadalafil was approved by the EU, the medicine appeared on the markets of Europe, USA, New Zealand and Australia.

Cialis is joint development of corporation ICOS and American pharmaceutical company Eli Lilly. For millions of men this new medicine became a chance to find harmony in their sexual lives. The main advantage of medicine is the duration of 36 hours! This allows planning sexual life. A man may take a medicine in the morning and to have a romantic date in the evening.

As Cialis treats ED, it is recommended to limit sexual activity if you have the following diseases:

  •           myocardial infarction;
  • –          heart failure;
  • –          cardiac arrhythmias, too low or too high blood pressure;
  • –          insult.

Cialis may lead to a drop of blood pressure, especially in combination with nitrates, poppers (non-narcotic drugs to stimulate central nervous system) and medicines for treatment of prostatic hyperplasia. The drop of blood pressure is dangerous, because it may result to fainting, heart attack or insult.

Some antifungal and antiviral medicines enhance the effect of ED medicine. Antacids (medicines for reducing gastric acidity) increase the period of Cialis absorption. So if you are taking any medicines and Cialis, please, consult your doctor about the possible consequences. It especially concerns cardiac medicines and nitrates!

As there is no information about the combination of Cialis and other kinds of medicines for treatment of ED, to take them simultaneously is not recommended (including dietary supplements, because you do not know how to react components of supplement and tadalafil). As Cialis is processed by the kidneys and decomposes in the liver, it is not recommended to use this medicine if you have renal and hepatic failure.